Functional T Cell Assays for Food Allergy

Funded by the Food Allergy Fund

Dr. David Hill, Perelman School of Medicine at the University of Pennsylvania as Principal Investigator

This project aims to develop functional T cell blood assays for use in the diagnosis, management, and monitoring of food allergy. The use of such clinical tests would significantly reduce the time to identify and to determine dietary removal of allergenic foods for non-IgE-mediated food allergies such as eosinophilic esophagitis (EoE) and food protein-induced enterocolitis (FPIES). These tests would also increase our ability to monitor pathogenic and regulatory T cell responses during oral immunotherapy (an FDA-approved therapy for anaphylactic food allergy).

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